Marco Bezzecchi (Mooney VR46 Racing Team) ended FP4 at the top of the timesheets with a 1:59.925, as Fabio Quartararo (Monster Energy Yamaha MotoGP™) suffered a Turn 8 crash at the PETRONAS Grand Prix of Malaysia. The Frenchman was unhurt as Marc Marquez (Repsol Honda Team), teammate Pol Espargaro, and Prima Pramac Racing duo Jorge Martin and Johann Zarco also suffered small crashes in the 30-minute stint.